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Some functions that choline serves in the body are: Production of sphingomyelin and phosphatidylcholine, which are needed to maintain cell membrane integrity

They also contain vitamin B12 to stimulate your metabolism and give you a boost of energy

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In addition, the concentration of 5MTHF in the CSF is lower than normal in patients with idiopathic cerebral folate deficiency, and some patients also have reduced concentrations of CSF 5-hydroxyindoleacetic acid and biopterin

Acute symptoms such as fatigue may improve within days, whilst neurological symptoms like paraesthesia typically require weeks to months of treatment