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IHC analysis This study was approved by the Institutional Committee of Nanfang Hospital, Southern Medical University, and all patients were fully informed and provided written informed consent before surgery

10.3389/fphar.2021.672769 12 ChoH

We further hypothesized that melatonin supplementation could improve the success rate of ART by increasing the quality of oocytes and embryos, increasing pregnancy rates, reducing oxidative stress, and promoting overall reproductive health

Microscopic observation and imaging were performed, and protein expression levels were quantitatively analyzed using ImageJ software

Kowdley KV, Bowlus CL, Levy C, Akarca US, Alvares-da-Silva MR, Andreone P, Arrese M, Corpechot C, Francque SM, Heneghan MA, Invernizzi P, Jones D, Kruger FC, Lawitz E, Mayo MJ, Shiffman ML, Swain MG, Valera JM, Vargas V, Vierling JM, Villamil A, Addy C, Dietrich J, Germain JM, Mazain S, Rafailovic D, Tadd B, Miller B, Shu J, Zein CO, Schattenberg JM, The New England journal of medicine 2023 Nov Open-label, clinical trial extension: Two-year safety and efficacy results of seladelpar in patients with primary biliary cholangitis