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NMR analysis of 15 - b20 revealed unexpected amine selectivity by Cp1D toward 4-(2-aminoethyl)aniline, as the amide bond was only formed through the aniline amine instead of the more nucleophilic aliphatic amine

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Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against Endoplasmic reticulum stress and steatosis in mice

Pseudokinase PTK7 intervenes in the regulation of the Wnt/-catenin pathway signaling, so the inhibition of the PTK7/-catenin interaction could represent a new therapeutic strategy to inhibit CRC cell growth ( 5 Challenges and future perspectives During the progression of CRC, dysregulation of the Wnt/-catenin signaling pathway promotes tumor invasion and metastasis, accelerating disease development

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