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10.3389/fpls.2025.1617432 47 SolgiE.Esmaili-sariA.Riyahi-bakhtiariA.HadipourM

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FIGURE 1 4 Traditional Chinese medicine (TCM) compounds treat AD through the MAPK signaling pathway A substantial body of research has demonstrated that plant-derived natural compoundssuch as flavonoids, alkaloids, saponins, and phenolic acidsmodulate neurotransmitter levels through multiple signaling pathways and cascade reactions, thereby improving behavioral performance and memory function, reducing A protein deposition, inhibiting acetylcholinesterase (AChE) activity, preventing neuronal apoptosis, and enhancing cerebral antioxidant capacity