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While much of the research remains in preclinical stages, early findings are promising

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311,312,313 It has recently been demonstrated that MIF inhibits the GC-induced leucine zipper (GILZ) expression via a unique set of effects on transcription factor expression and phosphorylation, and regulation by MIF of MKP-1 and MAPK activation are mediated through GILZ (Fig

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doi:10.1210/edrv-14-1-107 [2] Hu S, Rayman MP