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Therefore, ME2 has two functions in mitochondria: the first is producing pyruvate and NADH to generate ATP through oxidative phosphorylation, and the second is generating NADPH to counteract ROS

10.1016/0048-4059(83)90020-6 Physiol

its metabolites also cause DNA damage and mutations in bladder epithelial cells (Mastrangelo et al., 1996)

After quality control, pre- and post-treatment measurements of IC/VC VOIs were available for 52/53 and 46/53 patients, respectively, whereas data at both time points were available for 43/50 patients

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