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GHK-Cu is a copper-bound tripeptide reference compound commonly utilized in controlled laboratory and in-vitro research environments examining peptide-mediated cellular signaling, copper-dependent biochemical pathways, and tissue-related research models

CRL-1435) were cultivated in RPMI 1640 medium (Sigma-Aldrich) supplemented with 10% foetal bovine serum (FBS, Vitrocell)

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We hypothesize that phosphorylation of Ser-189 alters the conformation of this disordered region in AATF, thereby affecting its interaction with XRCC4 by interfering with the helical domains of both proteins

doi: 10.1186/s13059-023-02931-y 46 XiongJHeJZhuJPanJLiaoWYeHet al