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Gaur et al reported that the Dicer enzyme can increase bone mass during aging in mature osteoblasts expressing osteocalcin

Collectively, our data reveal that Y37P substitution in Cagri (from Amy) promotes differential engagement of the Cagri peptide with each RAMP that contributes to distinct conformational dynamics from those observed for each individual rAmy-bound AMYR complex

Naviaux et al., 2019

During injury states, the peptide helps regulate the inflammatory response, reducing the overproduction of pro-inflammatory cytokines that can perpetuate pain and tissue damage

T 2 relaxation data were processed using the MestReNova 14.1 data analysis module to obtain integrals of individual 1 H-NMR signals, which were used to calculate R 2 with the equation I = I 0 e (tR2)