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LH/FSH dysregulation an elevated LH-to-FSH ratio produced by abnormally rapid GnRH pulse frequency in the hypothalamus, creating a hormonal environment that stimulates androgen production while suppressing follicle maturation.[3] Chronic low-grade inflammation elevated CRP, IL-6, and TNF-, even in lean women with PCOS and in the absence of obesity, suggesting that inflammation is a core feature, not a secondary consequence of excess weight

Breathing through the mouth dries out the oral tissues

[15] It is also contraindicated for patients hypersensitive to cobalt and cyanocobalamin

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203,204,205,206 Studies have shown that FMT in combination with probiotic therapy at a ratio of 9:1 can significantly reduce intestinal barrier damage, decrease the levels of TNF- and IL-6 in colon tissue, and alleviate UC symptoms