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Obesity (Silver Spring) 20 (4), 738747

Manipulating the microbiome to favor GLP-1-producing bacteria could amplify tirzepatide effects

Frente a pptidos metablicos como MOTS-c, que acta como pptido derivado mitocondrial modulando AMPK y homeostasis energtica, 5-Amino-1MQ comparte la convergencia sobre el eje AMPK pero difiere radicalmente en naturaleza qumica: es una molcula pequea permeable a membrana y no un pptido