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Data recorded in medical charts are not collected as systematically as they are in clinical trials, he added, so more rigorous data collection on long-term side effects may be warranted

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R., Jaron, K

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Purines in the eye: recent evidence for the physiological and pathological role of purines in the RPE, retinal neurons, astrocytes, Muller cells, lens, trabecular meshwork, cornea and lacrimal gland

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The strongest long-term evidence points to cardiovascular associations, but association is not the same as proof of cause

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