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Activation of Nrf2 to prevent cancer development 2

137 In GC, the novel natural product inhibitor of STAT3 termed XYA-2 might exert its anticancer activity by synergistically inhibiting the expression of MYC and ZIP10, two downstream genes of STAT3 in vitro and in vivo

This bidirectional interplay underscores the role of the gut as both a responder and a driver in multiorgan networks, with implications for a wide array of diseases