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The release and excessive accumulation of collagen fibers caused by overactivated fibroblasts, which are marked with fibroblast activation protein (FAP), lead to pathological changes in the extracellular matrix (ECM) and persistent inflammation, resulting in a vicious cycle of cellular activity and extracellular fibrosis 3,4,5,6,7

Mohtashami, Z., Singh, M

In contrast, M2 macrophages are promoted by interleukin-4 (IL-4), interleukin 13(IL-13), and immune complexes (ICs) and are associated with anti-inflammatory functions, including the resolution of inflammation and tissue repair 8

Most peptides reconstituted in bacteriostatic water remain stable for 3-4 weeks at this temperature

Rajib Ghose General Physician/ Internal Medicine Specialist 25 Years MBBS East Midnapore VIVEKANANDA SEBA SADAN, East Midnapore Dr