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Studies show that glutathione can improve insulin resistance and prevent type 2 diabetes

The purine targeted by hydroxyl radical generates various purine adducts like 2,6-diamino-4-hydroxy-5-formamidopyrimidine, 8-hydroxy deoxy adenosine, and 8-hydroxydeoxy guanosine

Xia N, Strand S, Schlufter F, Siuda D, Reifenberg G, Kleinert H, Frstermann U, Li H (2013) Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol