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Salvianolic acid B (SalB), a polyphenolic compound from Salvia miltiorrhiza , improves mitochondrial function in MPP+-treated N2A cells by restoring mitochondrial membrane potential, reducing ROS production, enhancing mitochondrial biosynthesis, and activating the AMPK/SIRT3 signaling pathway (Zhao et al

These data mutually demonstrated that the AMPK/mTORC1 signaling pathway functions as a in adynamic and metabolic control, where the stability between these two contrasting cascades regulate tumor cell outcome and metabolic elasticity, emphasizing the essential for accuracy therapeutic methods that need for cancer-specific metabolic addictions and microenvironmental restrictions

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[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Choi IY, Lee SP, Denney DR, Lynch SG