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For example, although the tight control of synovial inflammation has proven to arrest the progression of bone erosions in some cases (for instance TNF- inhibitor has a promising effect on mitigating bone erosion in RA) 15 , the use of corticosteroids and MTX causes even more severe bone destruction in RA patients 16,17

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10.1016/j.repbio.2019.12.009 193 SklanE