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IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms

Immunofluorescence staining and western blotting were used to assess protein expressions including GLT1, B-cell lymphoma 2 (BCL2), BCL2 associated X (BAX), and cleaved caspase 3 (CCP3)

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This includes managing stress through relaxation techniques like meditation or deep breathing, getting regular exercise, maintaining a healthy weight, and avoiding stimulants like caffeine