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Treatment with simvastatin caused a dose-dependent decrease in cell viability, reduced mitochondrial CoQ 10 content, and reduced the oxygen consumption rate

Additionally, the encapsulated formulation demonstrated significant protective effects against hyperglycemia-induced retinal microvasculopathy in DR [104]

The results demonstrated that the combined regimen significantly improved tinnitus-related scores and TCM syndrome integrals, enhanced hemorheological conditions, and reduced oxidative stress and inflammatory markers compared to cobamamide alone