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Over the past decade, considerable progress has been made in directing ESCs toward primordial germ cell (PGC)-like cells and, under optimized conditions, toward functional gametes (193, 194)

It is important to note that a recent study has demonstrated a significant upregulation of NRF2, HMOX-1 and NQO-1 mRNA expression, as well as an increase in HMOX-1 and NQO-1 protein levels in the spinal cord of ALS patients (Lastres-Becker et al., 2022)

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In human beta cells, proprotein convertase 1/3 (PC1/3) is mainly responsible for C-peptide release, while in rodent beta cells, its paralogue proprotein convertase 2 (PC2) also participates in this process [72]

El glutatin (GSH) es una molcula formada por la asociacin de 3 aminocidos: cido glutmico, cistena y glicina