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Considering that spermatozoa are exposed to both internally produced ROS and those present in the seminal plasma due to external factors such as smoking, alcohol, heat, and others, determining their levels is of fundamental importance as they can be a cause of reduced sperm quality with a decrease in motility and vitality and increased sperm DNA fragmentation [38,39,40]

Mitochondrial metabolism of reactive oxygen species

11 Lower glutathione levels have also been linked to worse outcomes in infections, including HIV and influenza, likely due to impaired immune cell activity and heightened oxidative stress

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It may also help to use a gentle cleanser before applying GHK-Cu and follow it with a basic, noncomedogenic moisturizer