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However, despite the mitochondrial release of cytochrome c [107,113] during APAP-induced liver injury, there is no activation of caspases [114,115] and all morphological characteristics of necrosis including cell and organelle swelling, cell contents release and karyolysis are evident both in vivo and in vitro [116-118]

One of the mechanisms of action of resveratrol on the nerve regeneration process is associated with its antioxidant ability, due to the leveling of the content of hydroxyl, superoxide, and other radicals

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