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However, GPx4 expression has been shown to affect various cellular signaling events that may at least partly contribute to the developmental abnormalities observed in embryos with impaired GPx4 expression

Among these, the RF model demonstrated the best overall predictive accuracy and robustness

Kim, D, Paggi, JM, Park, C, Bennett, C & Salzberg, SL Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

It is mainly associated with hypotension, hyperkalemia, renal impairment, and, less commonly, angioedema