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In multiple animal models, a downregulation of RBFOX2 has been shown to lower heart rate, cause myofibrillar disarray and result in heart failure (179, 180)

doi: 10.1111/nph.16636 15 JenkinsNLJamesSASalimASumardyFSpeedTPConradMet al

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To better understand the role of sulfide catabolism and potentially develop countermeasures against H 2 S poisoning, we recently launched a project to develop novel H 2 S-specific scavengers in collaboration with Xian laboratory [90]

Furthermore, the supplement of NAC, a glutathione precursor disrupting the cooperation of BSO and DPI, significantly attenuated the cytotoxic effects of the combination therapy