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In conclusion, SAC exerts antioxidant and anti-ferroptotic effects by modulating the Keap1/Nrf2/GPX4 signaling axis

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In addition, breast cancer cells divert excess PUFAs into TAGs and store them in LDs, effectively buffering oxidative stress from an excess of lipids and sustaining cell viability under the pressure of hypoxia and ferroptosis 105,106

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Amino acid metabolism in drug resistance With increased demand for nutrients during chemotherapy, cancer cells have been shown to upregulate L-type amino acid transporter 1 (also known as SLC7A5), which helps in the transportation of branched chain amino acids, such as leucine, isoleucine, valine, and bulky amino acids such as phenylalanine, tryptophan, tyrosine, methionine, glutamine, asparagine, and histidine, and is associated with TNBC [31, 122, 123]

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Blood tests play a crucial role in the safe administration of supplements

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