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Clinical translation requires addressing challenges including cell-type specificity, development of disease-specific ferroptosis biomarkers, optimization of combination regimens, and careful safety assessment to avoid unintended effects such as myelosuppression or hepatorenal toxicity

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10.1016/0005-2728(94)90173-2 17 KaronenM.MattilaH.HuangP.MamedovF.StyringS.TyystjrviE