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Which means that there is no need to dissolve it

Notably, principal component analyses of these H3K36me2 CUT&Tag data support the interpretation that targeting of Nsd2 reverses plasticity and neuroendocrine states at the epigenomic level (Extended Data Fig

10.1016/j.exger.2024.112539 92 SantamaraG.Fernndez-GorgojoM.Gutirrez-AbejnE.GarcaG

TMT ratio check The combined and dried ratio check sample was re-dissolved in Buffer A (5% CH 3 CN, 95% water, 0.1% formic acid, 20 L) and desalted using C18 stage tips prepared in-house using 3 C18 discs (3 M Empore) stacked in 200 L pipette tips

The available evidence suggests that such biotechnological methods not only increased the quantity and availability of PPs for industrial, food and medicinal purposes (360, 381, 382), but also expedited the number of scientific investigations conducted on PPs to find the most potent metabolites for large-scale applications (361)