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The objective of this narrative review is to delineate the mechanisms driving RS and critically evaluate the consequences of excessive antioxidant supplementation on male reproductive function

The study, its participants and their potential for genetic research on health and illness

New mutations may occur frequently, leading to a heterozygous state in which two or more mtDNA sequence variants (i.e., wild type and one or more mutants) coexist

Citing the available literature, Deepankar et al

The cell contains millimolar concentrations of GSH (up to 10 mM) that is maintained in this reduced form by a cytosolic NADPHdependent reaction catalysed by glutathione reductase