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I know there are quite a few variables with oral bioavailability, but assuming taken fasted,

B12 and Folic Acid Injections Common nutrient deficiencies of B12 and folic acid are often found in vegetarians and vegans who are not supplementing properly

B12 InjectionB12 injections provide a concentrated dose of vitamin B12, an essential nutrient that supports energy production, metabolism, and overall health

Vitamin B12 shots improve cognitive function and reduce the risk of dementia or Alzheimer's disease

it is likely to translate into better real-world adherence, and better adherence is the most important determinant of long-term therapeutic outcomes in chronic disease management