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A Phase II study in non-small-cell lung cancer reported encouraging results with a disease control rate of 87% (Mayor, 2011)

The invasion index was used to assess cancer cell migration and invasion (invasion index = /), and the growth index was used to evaluate the ability of dorsal root ganglion axons to grow toward cancer cells (outgrowth index = /) (Supplementary Fig

Ondanks de korte plasma-halfwaardetijd persisteren de downstream biologische effecten in weefsel aanzienlijk langer, consistent met een signaalcascade in plaats van directe dosis-respons-activiteit

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