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The primary source of ROS leading to chondrocyte death and exacerbating inflammatory reactions, thereby aggravating articular cartilage degradation, is mitochondrial dysfunction

In one study, in pediatric peritoneal dialysis, patients observed reduction of apolipoprotein B levels with 50 mg/kg per day of l-carnitine supplementation for a month [107]

This period allows the mice to adjust to their new environment, ensuring natural responses

showed that supplementation with lutein (10 mg), zeaxanthin (2 mg), and meso-zeaxanthin (10 mg) for 12 months improved cognitive abilities and episodic memory in participants [26]

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