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The histidine and lysine residues create a binding site with very high affinity for copper(II) ions, forming the GHK-Cu complex

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Studies conducted in mice and human foreskin fibroblasts have revealed that S-acetyl-glutathione molecules are taken up directly by cells with subsequent conversion to glutathione by cleavage of the acetyl bond within the cell

[DOI] [PubMed] [Google Scholar] 147.Rosenblat M., Volkova N., Coleman R., Aviram M