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140 Thus, cysteine contributes to the inhibition of ferroptosis both as a component of glutathione, which facilitates the scavenging of lipid peroxides by the phospholipid hydroperoxidase glutathione peroxidase 4 (GPX4), and as a substrate of NFS1

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Cells dosed with a serial dilution of BSO showed no cytotoxicity compared to the vehicle control, indicating that the compound did not kill the cells (Figure 5, Panel A)