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Endogenous causes (medical conditions) When B12 is elevated without supplementation , it can indicate that the body is releasing stored B12 from damaged tissues, producing excess B12-binding proteins, or failing to clear B12 normally

pubmed.ncbi.nlm.nih.gov/29986520 Pickart L

Its copper delivery function is biologically significant because copper is a cofactor for lysyl oxidase (essential for collagen cross-linking), superoxide dismutase (antioxidant defense), and cytochrome c oxidase (mitochondrial energy production)

and endpoint B) added with 500 l of RPMI 1640 culture medium with cyanocobalamin (Merck) to a final concentration of 1 nM

In addition to promoting tissue repair, it also alleviates joint pain and arthritis