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Conclusion Pregabalin treatment induced significant reproductive toxicity in rats, characterized by decreased body and testicular weights, increased oxidative stress, inflammation, and apoptosis, accompanied by disruption of the hypothalamic-pituitary-gonadal axis

Goel P, Chakrabarti S, Goel K, Bhutani K, Chopra T, Bali S (2022) Neuronal cell death mechanisms in Alzheimers disease: an insight

NF-B is also involved in this process (Yang et al., 2012a)

Additionally, glutathione injection is essential for restoring mitochondrial function, which is crucial for efficient cellular signaling and metabolic processes

Sulfur from sulfur-containing amino acids, namely cysteine, is also incorporated into tRNAs known as tRNA thiolation