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Research-Use-Only (RUO) Regulatory designation indicating that a compound is intended solely for laboratory and preclinical research applications

Because of the side effect profile and the fact that anyone taking Accutane has to be monitored with frequent lab work, it tends to only be worth it for people with moderate to severe acne, says Shah

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Cells were then treated (duplicate wells/treatment) with stuarosporine (1 M) for 24 h [21] or H 2 O 2 (1002500 M, Sigma-Aldrich) for 2 h at 37 C a 30 min pre-treatment with inhibitors of cell death: liproxstatin (LPX, 10 M, Sigma-Aldrich) and necrostatin-1 (25 M) [22]

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