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Clinical and molecular characterization of classical-like Ehlers-Danlos syndrome due to a novel TNXB variant

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It was considered that since smaller permeates have a lower permeation resistance in narrow channels when the sizes of permeates and channels are comparable 44,45 , smaller AuNPs showed a higher tendency for permeability through gaps opened in the BBB

2013;8 doi: 10.1371/journal.pone.0075667

Treatment with A 40 oligomers significantly reduced the cell viability and apoptosis of astrocyte brain cultures and increased oxidative modifications of DNA, lipids, and protein, enhanced pro-inflammatory cytokine release and increased the activity of the proteolytic matrix metalloproteinase enzyme, matric metalloproteinase (MMP)-2 and reduced the activity of MMP-9 after 24 h