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Common Side Effects These side effects are typically mild and improve as your body adapts: Nausea and vomiting A common side effect, especially when increasing dosage

Lemberger, L

17 Moreover, other trials as the SUSTAIN-6 trial showed that semaglutide, another GLP-1RA also reduced the risk of MACE by 26% and non-fatal stroke by 39% in patients with T2DM

Analysis of the data indicates that short-term treatment with RM-493 increased resting energy expenditure significantly (by 6.4% vs placebo), thus suggesting RM-493 may be clinically effective for treating obesity