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Dirty bileor bile that hasnt been cycled out regularlycan be reabsorbed and contribute to the bodys toxic burden

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In these studies, impairment in mitochondrial function such as reductions in the activity of electron transport chain (ETC) enzymes, specifically complex I activity, and reduction of N-acetyl aspartate levels were found in the hippocampal region of the brain (Kunz et al., 2000

Dexrazoxane (DXZ), the only FDA-approved agent for preventing doxorubicin (DOX)-induced cardiotoxicity, exerts its protective effects by chelating mitochondrial iron and mitigating oxidative stress [37]