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Stuart, T et al

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Dysregulated iron homeostasis constitutes the fundamental basis for ferroptosis initiation ( 4.1 Molecular pathways governing ferroptosis cell death Iron is a critical driver of lipid peroxidation and subsequent ferroptosis within cellular environments ( Diminished activity of the cystine/glutamate antiporter (system Xc-) serves as the initial trigger for ferroptosis ( Ferroptosis substrates primarily include polyunsaturated fatty acids (PUFAs, characterized by their abundance of double bonds), free polyunsaturated fatty acids such as oxidized arachidonic acid, and adrenal hormones

however, direct correlations between TNF levels and PA stiffness in PH have yet to be established

Ulcerative colitis and erythrocyte G6PD deficiency: salicylazosulfapyridine-provoked hemolysis