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Abbreviations AA2: Aldosterone to angiotensin II ratio ACE: Angiotensin-converting enzyme ACE2: Angiotensin-converting enzyme 2 ACE-S: Angiotensin-converting enzyme surrogate ALT-S: Alternative RAAS activation marker CHF: Congestive heart failure NEP: Neutral endopeptidase PRA-S: Plasma renin activity marker RAAS: Reninangiotensinaldosterone system References Borgarelli, M