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Multiple molecular subtypes of GST have shown the ability to prevent skin, colon, and liver cancer initiation in mice exposed to carcinogens or lacking tumor suppressors ( Potential confounding factors, limited sample sizes, and other biases in observational studies make it difficult to derive an undetermined causal conclusion between antioxidants and cancers

When the brain suffers injury, BDNF levels in the affected region typically drop, leaving neurons vulnerable to apoptosis

Concurrently, SA activates the PI3K/Akt/NF-B axis to upregulate antioxidant enzymes (SOD, catalase) and enhances FOXO-mediated redox homeostasis through NAD+-dependent SIRT1 activation (Fig

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Mice were killed at multiple time points up to 24 h after APAP treatment