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Disclosures: Majd Aboona: Nothing to Disclose, Leith Ghani: Nothing to Disclose, Pooja Rangan: Nothing to Disclose, Vincent Chen: AstraZeneca: site PI on industry-sponsored trial, Ipsen: site co-I on industry-sponsored trial, Kowa: site co-I on industry-sponsored trial, Cheng Han Ng: Nothing to Disclose, Daniel Huang: Nothing to Disclose, Mark Muthiah: Lerna Bio: Stock privately held company, Olympus: Speaking and Teaching, Boston Scientific: Speaking and Teaching, Novo Nordisk: Grant/Research Support, Echosens: Grant/Research Support, Gilead: Advisor, Donghee Kim: Nothing to Disclose, Moises Nevah Rubin: Nothing to Disclose, Ma Ai Thanda Han: Nothing to Disclose, Michael Fallon: Nothing to Disclose, Karn Wijarnpreecha: Nothing to Disclose 1123 RISK OF COMORBID MENTAL HEALTH CONDITIONS IN CHILDREN WITH METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE Sheila Noon 1 Nhat Thai 2 Kimberly Newton 3 Nidhi Goyal 3 Benjamin Maxwell 3 Elizabeth Yu 3 Warren Shapiro 4 Jeffrey Schwimmer 3 , 1 University of California, San Diego School of Medicine, 2 San Diego State University, 3 Rady Children's Hospital San Diego, 4 Kaiser Permanente San Diego Background: Steatotic liver disease (SLD) affects nearly 1 in 10 children in the United States

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Lower levels of testosterone can have many unwanted effects, including decreased sexual desire, lower energy levels, poor concentration, and depression

Based on the molecular functions of mitochondrial proteins with significant MR analysis, we found that T2DKA is primarily associated with imbalances in both mitochondrial function and capacity, while UNDKA is mainly related to imbalances in mitochondrial capacity