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During systemic inflammation, the BBB is impacted via numerous processes, such as, activation of matrix metalloproteinases (MMPs), oxidative stress and free radical damage, and direct effects of circulating cytokines on tight junction proteins

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11 Conclusion In this paper, we have investigated the role of deuterium in mitochondrial dysfunction, and the potential role of amyloidogenic proteins in sequestering deuterium within plaque deposits, both in the brain and in the pancreas

Maenner et al., 2023)

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