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These cytokines and chemokines subsequently recruit and activate immune cells, perpetuating the inflammatory cascade in cardiovascular tissues

With 335 sequences, proteases comprise 2.5% of the putative proteome (Supplementary Table 18), consistent with the proportion in other organisms (15%), but this is only one-third of that in humans (945 sequences, if A2 family retrovirus and retrotransposon proteases are included)