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Subcutaneous injection bypasses first-pass hepatic metabolism and delivers near 100% bioavailability, which is why all published rodent studies use injection rather than oral dosing

Preliminary results from Phase III clinical trials on BNT162b2, published in October 2020, indicated potential for its safety and efficacy

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People following a diet low in B12 or those with conditions that hinder B12 absorption are also excellent candidates for these shots

So now we have at least 3 different ways that thyroid patients can become B12 deficient ranging from the bacteria in their gut to the speed of their GI tract to direct damage from their stomach from their immune system