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L-Carnitine improves the metabolism of BCAAs, reducing the accumulation of their toxic byproducts and helping to maintain muscle function and reduce muscle damage

In addition to being found in a wide range of foods, it is also commonly available as a dietary supplement

Nevertheless, the pooled analysis of 16 trials suggested improvements in the summary measure of patients' global functioning (assessed with the Clinical Global Impressions [CGI-I] scale) after 12 and 24 weeks of (but not after 52 weeks) of ALCAR treatment (1-3 g/day) and in cognitive performance (assessed with the Mini-Mental State Examination [MMSE] scale) after 24 weeks (but not at 12 or 52 weeks) (104)

The findings indicated that capsaicin led to more significant pain relief over the 4 to 12 week period

These measurements provide a snapshot of mitochondrial fatty-acid oxidation and amino-acid catabolism, helping researchers interpret metabolic pathways and energy regulation