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The authors found that the seizure duration can be shortened upon activation of ChR2- or HR channels in both laterally and medially localized Purkinje cells, but that the seizure occurrence could only be dampened when the midline Purkinje cells were optogenetically excited

Paeonol reduces IL-beta production by inhibiting the activation of nucleotide oligomerization domain-like receptor protein-3 inflammasome and nuclear factor-kappaB in macrophages