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Beneficial effect of Corni Fructus, a constituent of Hachimi-jio-gan, on advanced glycation end-product-mediated renal injury in Streptozotocin-treated diabetic rats

To exploit this vulnerability, FCSP@876 MOFs were developed, combining a ferroptosis-inducing MOF with the GLUT1 inhibitor BAY876

The gradient started with 55% A, progressed to 95% A over 3 min, and was maintained for 1.5 min

Subcellular fractionation confirmed that each of these ORFcoq3 double mutants have decreased uptake of exogenous CoQ 6 in mitochondria, Golgi, vacuole, and plasma membrane compared to WT and coq3 controls, further illustrating the impact of disrupting these trafficking pathways in CoQ 6 uptake

Maier, N