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The degradation of ferritin can be completed through ferritinophagy, a selective autophagy process mediated by Nuclear Receptor Co-activator 4 (NCOA4)

10.1016/j.febslet.2007.05.071 FEBS Lett

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In the therapeutic-response arena, mucosal eosinophil abundance and serum eotaxin-1 levels have been strongly associated with vedolizumab efficacy [546]