A 2015 double-blind, randomized and placebo-controlled study conducted in India evaluated the efficacy of ashwagandha extracts in enhancing cardiorespiratory endurance in 50 healthy adult athletes
Our work explores the synergistic combination of L-carnosine and copper, yielding nanoclusters (CuL) that show: Enhanced cytotoxicity toward lung cancer cells (A549) Minimal toxicity to normal cells Nanomolar-level sensitivity for glutathione detection Strong potential for theranostic applications Grateful to my co-authors, collaborators, mentors, Netaji Subhas University of Technology (NSUT, Formerly NSIT), the Indian patent office, the patent agent, and the editorial team for their support throughout this journey
Ethics declarations Competing interests The authors declare that they have no competing interests
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Abbreviations ACTH: adrenocorticotropic hormone CF: chronic fatigue CFS: chronic fatigue syndrome CMI: cell-mediated immune CNS: central nervous system CRH: corticotropin-releasing hormone CVD: cardiovascular disease DISC1: disrupted-in-schizophrenia 1 EBV: Epstein-Barr virus HHV: human herpesvirus HPA: hypothalamic-pituitary-adrenal IBS: irritable bowel syndrome IL: interleukin IL-1RA: IL-1 receptor antagonist LPS: lipopolysaccharide MDA: malondialdehyde ME: myalgic encephalomyelitis NF: nuclear factor O&NS: oxidative and nitrosative stress PEM: post-exertion malaise lasting more than 24 h PGs: prostaglandins PUFAs: polyunsaturated fatty acids RNS: reactive nitrogen species ROS: reactive oxygen species SF-36: 36-item short-form health survey SNS: sympathetic nervous system TDO: tryptophan 2,3-dioxygenase TGF: transforming growth factor Th: T helper TNF: tumor necrosis factor